The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines - preprint, as discussed on the tin
Here, by using an in vitro cell line, we report that the SARS-CoV-2 spike protein significantly inhibits DNA damage repair, which is required for effective V(D)J recombination in adaptive immunity. Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA damage repair by impeding key DNA repair protein BRCA1 and 53BP1 recruitment to the damage site.
Work on and with adenovirus vectors is premised on the unproven claim that these vectors are safe because adenovirus DNA would "not integrate"into the recipient cells’ genomes. There is no solid evidence for this interpretation. Hence, the following synopsis of our work and that of others takes issue with this notion (Doerfler et al., 1984). The problems encountered in gene therapeutic procedures of the past (Samanathan et al, 2020) and presently with adenovirus vector-based SARS-CoV-2 vaccines will require a thorough re-evaluation of the drawbacks that adenovirus vector systems entail.
Cutaneous T-cell lymphoma (CTCL) exacerbation after viral vector COVID-19 [gene therapy] - A peer-reviewed description of the jab making cancer worse.
An observational study of breakthrough SARS-CoV-2 Delta variant infections among vaccinated healthcare workers in Vietnam published by EClinicalMedicine, a publication of The Lancet. Quantifies a difference in viral loads between AstraZeneca breakthrough-Delta infections and unjabbed infections.
We found viral loads of breakthrough Delta variant infection cases were 251 times higher than those of the infected cases detected during the early phase of the pandemic in 2020, with high viral loads recorded around 2-3 days before and after the development of symptoms.
Certain COVID-19 Vaccine Lots Are to Blame for Majority of Adverse Events in Public Data - Independent research allegedly pulled from VAERS (procedure available on request, which is a bit of a red flag, but not necessarily) which suggests that adverse effects from Pfizer and Moderna derive from particular lots of the preparation.
Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues from Proceedings of the National Academy of Sciences of the United States of America.
We show here that SARS-CoV-2 RNA can be reverse-transcribed and integrated into the genome of the infected cell and be expressed as chimeric transcripts fusing viral with cellular sequences. Importantly, such chimeric transcripts are detected in patient-derived tissues. Our data suggest that, in some patient tissues, the majority of all viral transcripts are derived from integrated sequences.An angry letter from other scientists tries to cast shade but the authors hold their ground.
Parry et al. state that “SARS-CoV-2 integration into the host genome is unlikely.” Our response is that the “percent of library” calculation is not an estimate of integration frequency, which requires consideration of whole-genome sequencing (WGS) coverage. We identified integration events and observed two to five integrations per 10,000 cells at the current sequencing depth (Table 1). This is similar to the estimated integration frequency of lymphocytic choriomeningitis virus after acute infection (3). “Low frequency” of integration events cannot be interpreted as “unlikely.”
1000 Covid Stories - a crowdsourced aggregation of experiences with COVID and the vaccines. Typically heterodox. Site is focused on the kinds of stories that are being censored.
Intravenous injection of COVID-19 mRNA [gene therapy] can induce acute myopericarditis in mouse model in Clinical Infectious Diseases. Describes a model within which the reports of myopericarditis are explained, as well as procedural enhancements to the vaccination process to lessen damage.
Pfizer/Biontech's corporate safety evaluation of their experimental gene therapy injection. Funded by the manufacturers.
Moderna's corporate safety evaluation of their experimental gene therapy injection. Funded by BARDA and NIAID. References ClinicalTrials.gov which gives the disclaimer:
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.This disclaimer goes on to explain:
Clinical trials provide the basis for the development and marketing of new drugs, biological products, and medical devices. Sometimes, the safety and the effectiveness of the experimental approach or use may not be fully known at the time of the trial. Some trials may provide participants with the prospect of receiving direct medical benefits, while others do not. Most trials involve some risk of harm or injury to the participant, although it may not be greater than the risks related to routine medical care or disease progression. (For trials approved by IRBs, the IRB has decided that the risks of participation have been minimized and are reasonable in relation to anticipated benefits.) Many trials require participants to undergo additional procedures, tests, and assessments based on the study protocol. These requirements will be described in the informed consent document. A potential participant should also discuss these issues with members of the research team and with his or her usual health care provider.
The spike protein of SARS-CoV-2 variant A.30 is heavily mutated and evades vaccine-induced antibodies with high efficiency published in Cellular & Molecular Immunology.
Worse Than the Disease? Reviewing Some Possible Unintended Consequences of the mRNA Vaccines Against COVID-19 from the International Journal of Vaccine Theory, Practice, and Research. Peer-reviewed. Quoting the abstract:
In this review we first describe the technology underlying these vaccines in detail. We then review both components of and the intended biological response to these vaccines, including production of the spike protein itself, and their potential relationship to a wide range of both acute and long-term induced pathologies, such as blood disorders, neurodegenerative diseases and autoimmune diseases. Among these potential induced pathologies, we discuss the relevance of prion-protein-related amino acid sequences within the spike protein. We also present a brief review of studies supporting the potential for spike protein “shedding”, transmission of the protein from a vaccinated to an unvaccinated person, resulting in symptoms induced in the latter. We finish by addressing a common point of debate, namely, whether or not these vaccines could modify the DNA of those receiving the vaccination. While there are no studies demonstrating definitively that this is happening, we provide a plausible scenario, supported by previously established pathways for transformation and transport of genetic material, whereby injected mRNA could ultimately be incorporated into germ cell DNA for transgenerational transmission. We conclude with our recommendations regarding surveillance that will help to clarify the long-term effects of these experimental drugs and allow us to better assess the true risk/benefit ratio of these novel technologies.
How the Amish Approached Herd Immunity (archive) - Exactly as it ought to have been done. Whole community shares communion cup, whole community gets coronavirus, whole community gets over it, "pandemic" becomes obsolete. God blesses his faithful with immunity.
Sharyl Attkisson's list of Chinavirus "vaccine" concerns. Very exhaustive, lots of studies.
Among SUD patients, the risk for breakthrough infection ranged from 6.8% for tobacco use disorder to 7.8% for cannabis use disorder, all significantly higher than the 3.6% in non-SUD population (p<0.001). Breakthrough infection risk remained significantly higher after controlling for demographics (age, gender, ethnicity) and vaccine types for all SUD subtypes, except for tobacco use disorder, and was highest for cocaine and cannabis use disorders (hazard ratio, HR=2.06, 95% CI: 1.30-3.25 for cocaine; HR=1.92, 95% CI: 1.39-2.66 for cannabis).
Increases in COVID-19 are unrelated to levels of vaccination across 68 countries and 2947 counties in the United States - Published in European Journal of Epidemiology.
At the country-level, there appears to be no discernable relationship between percentage of population fully vaccinated and new COVID-19 cases in the last 7 days (Fig. 1). In fact, the trend line suggests a marginally positive association such that countries with higher percentage of population fully vaccinated have higher COVID-19 cases per 1 million people.
"Physicians Declaration" from the Global Covid Summit, Rome, Italy. As of the time of writing, over ten thousand "doctors and scientists" have signed. Not sure how robust that community is, but regardless, the sentiment is on-point.
Within 8 weeks of the public offering of COVID-19 products to the 12-15-year-old age group, we found 19 times the expected number of myocarditis cases in the vaccination volunteers over background myocarditis rates for this age group. In addition, a 5-fold increase in myocarditis rate was observed subsequent to dose 2 as opposed to dose 1 in 15-year-old males.
Workers Who Maintain Supply Chains Warn of Worldwide ‘System Collapse’ by Jack Phillips of the Epoch Times.
Everything You Always Wanted to Know About Masks, and the Deadly Falsehoods Surrounding Them - by By James D. Agresti on JustFacts.com. Another example of good research.
India's Ivermectin Blackout - Part III: The Lesson of Kerala - a news article discussing India's use of Ivermectin.