Elsevier's "Pharmacological Research" has published an article on ivermectin this January, Ivermectin, a potential anticancer drug derived from an antiparasitic drug .
Ivermectin has powerful antitumor effects, including the inhibition of proliferation, metastasis, and angiogenic activity, in a variety of cancer cells. This may be related to the regulation of multiple signaling pathways by ivermectin through PAK1 kinase. On the other hand, ivermectin promotes programmed cancer cell death, including apoptosis, autophagy and pyroptosis. Ivermectin induces apoptosis and autophagy is mutually regulated. Interestingly, ivermectin can also inhibit tumor stem cells and reverse multidrug resistance and exerts the optimal effect when used in combination with other chemotherapy drugs.
Dr. Joseph Mercola details Pfizer's shady history. Exhaustively documented, plenty of references.
The European Society of Cardiology's Heart Failure journal is reporting that aspirin use is associated with increased risk of heart failure in certain "at risk" categories.
Aspirin use is associated with an increased risk of HF in patients receiving aspirin with or without a previous history of CVDs. In the absence of conclusive trial evidence, our observations suggest that aspirin should be prescribed with caution in patients at risk of HF or having HF.
Ivermectin: enigmatic multifaceted ‘wonder’ drug continues to surprise and exceed expectations from the Journal of Antibiotics.
Among SUD patients, the risk for breakthrough infection ranged from 6.8% for tobacco use disorder to 7.8% for cannabis use disorder, all significantly higher than the 3.6% in non-SUD population (p<0.001). Breakthrough infection risk remained significantly higher after controlling for demographics (age, gender, ethnicity) and vaccine types for all SUD subtypes, except for tobacco use disorder, and was highest for cocaine and cannabis use disorders (hazard ratio, HR=2.06, 95% CI: 1.30-3.25 for cocaine; HR=1.92, 95% CI: 1.39-2.66 for cannabis).
A Canadian website explores the link between cannabis use and psychosis